Molecular mechanisms of ovarian aging and female age-related fertility decline remain unclear. A unique multimodal atlas of the adult human brain, featuring anatomic and genomic data. We surveyed the single-cell transcriptomic landscape of ovaries from young and aged non-human primates (NHPs) and identified seven ovarian cell types with distinct gene-expression signatures, including oocyte and six types of ovarian somatic cells. Bocchi et al. M, mucosa; ME, muscularis externa; TC, taenia coli. The BrainSpan project is a detailed atlas of gene expression across human development. chart human intestinal morphogenesis across time, location, and cellular compartments using a combination of single-cell RNA sequencing and spatial transcriptomics. surveyed molecular features as the striatum develops in the human brain. The Cell Atlas provides high-resolution insights into the expression and spatio-temporal distribution of RNA and proteins in human cell lines. Non-Human Primate. BRAIN ATLAS. Developing Human Brain. (E) Cross-section of a human colon, which has a thicker muscular wall and mucosa compared with the mouse colon (D). Iran (Persian: ایران ‎ Irān [ʔiːˈɾɒːn] ()), also called Persia and officially the Islamic Republic of Iran (Persian: جمهوری اسلامی ایران ‎ Jomhuri-ye Eslāmi-ye Irān [dʒomhuːˌɾije eslɒːˌmije ʔiːˈɾɒn]), is a country in Western Asia.It is bordered to the northwest by Armenia and Azerbaijan, to the … ... An atlas of human glycosylation pathways enables display of the human glycome by gene engineered ... Citation Tools View Data More information: Pierfrancesco Pagella et al. use single-cell sequencing and immunohistochemical validation to create an atlas of early human brain development. Genome-wide mRNA expression is determined by deep RNA-sequencing in a panel of 69 cell lines , representing various cell populations in different organs and tissues of the human body. The NIH Blueprint Non-Human Primate Atlas characterizes the developing rhesus macaque brain. In the manuscript titled "Mouse Aging Cell Atlas Analysis Reveals Global and Cell Type Specific Aging Signatures", Zhang and et al. Mouse Brain Connectivity Cell Types Brain Observatory. Panels B and C are reproduced from “Comparative anatomy and histology: A mouse and human atlas” by Piper M. Treuting and Suzy Dintzis, 2012, with permission from Elsevier. The Human Lung Cell Atlas: A High-Resolution Reference Map of the Human Lung in Health and Disease. Version: 20.1 Atlas updated: 2021-02-24 release history Proteome analysis based on 26941 antibodies targeting 17165 unique proteins systematically explored the aging-related genes in 76 tissue-cell types from 23 tissues in 10 male and 6 female mice from the Tabula Muris Senis single-cell transcriptomic dataset. Schiller et al. HOME; Mouse Connectivity. Human Brain Atlas. Single-cell surveys of long intergenic noncoding RNAs revealed a progenitor for medium spiny neurons and provide insight into evolutionary divergence of this critical part of the brain. View Atlas. Published Online: Jul 2019 . The cell-based display of the human sialome provides a versatile discovery platform that enables dissection of the genetic and biosynthetic basis for the Siglec glycan interactome and other sialic acid–binding proteins. Eze et al. In the telencephalon, they discover a … Mouse Brain Developing Mouse Brain Mouse Spinal Cord. We perform single-cell transcriptomes of 84,363 cells derived from 15 tissue organs of one adult donor and generate an adult human cell atlas. Quercetin Enhances Ligand-induced Apoptosis in Senescent Idiopathic Pulmonary Fibrosis Fibroblasts and Reduces Lung Fibrosis In Vivo. TOOLS. Human Brain Developing Human Brain Glioblastoma Aging, Dementia and TBI. Fawkner-Corbett et al. View Atlas. A single-cell atlas of human teeth, iScience (2021).DOI: 10.1016/j.isci.2021.102405 The resulting online searchable atlas describes the principles of crypt-villus axis formation as well as neural, vascular, mesenchymal morphogenesis, and immune populations of the developing gut. Wagner J, Rapsomaniki MA, Chevrier S, Anzeneder T, Langwieder C, Dykgers A, Rees M, Ramaswamy A, Muenst S, Soysal SD et al (2019) A single-cell atlas of the tumor and immune ecosystem of human breast cancer. Cell 177: 1330 – 1345 Crossref CAS PubMed Web of Science® Google Scholar Deep in the brain, the striatum receives and coordinates inputs from other parts of the brain. a, Outline of the protocol used for scRNA-seq of human liver cells.Samples from liver resections were digested to prepare single-cell suspensions.
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